Brand Name: Folotyn®
Pralatrexate is a chemotherapy drug that works by preventing cancer cells from growing. It does this by preventing cancer cells from using a certain nutrient (folate).
Pralatrexate is given intravenously.
Folic acid and vitamin B12 supplements may also be prescribed during treatment with pralatrexate to reduce the risk of possible side effects.
Treatment with pralatrexate might improve symptoms of skin lymphoma and reduce skin lesions. Pralatrexate does not work in all patients. It is important to discuss with your physician whether this might be an appropriate therapy and what the expected results might be for your individual disease.
Because of how pralatrexate works, patients need supplementation with folic acid and B12 to prevent side effects.
The following is not an exhaustive list of the possible side effects. For a complete list of possible side effects, please see the manufacturer’s available information on the specific therapy.
Possible side effects may be nausea, vomiting, diarrhea, constipation, low blood counts, and mucositis (sores in the mouth).