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Treatment Options

Therapeutic Treatment Options for Cutaneous T Cell Lymphoma
This area attempts to provide patients and their family members with current information on the available treatments for CTCL.  This information is not meant to be all inclusive, but is rather a launching point for further inquiry.  This material should not substitute for thoughtful dialogue between patient, family and an experienced CTCL health care provider. 

Skin-Directed Therapies:
Topical therapies:
Topical Corticosteroids
Bexarotene Gel
Topical Chemotherapy
     Carmustine
     Mechlorethamine

Phototherapy:
UVB – Broad & Narrow Band
PUVA

Radiation therapy:
Local & Total Skin Electron Beam
Conventional Radiation Therapy

Systemic Therapies:
Targeted/ Biological / Immuno- therapies:
Oral Corticosteroids
Bexarotene (Targretin®) Capsules
Photopheresis
Interferons
Denileukin Diftitox (Ontak®)
Alemtuzumab (Campath-1H)
Vorinostat (Zolinza®)

HDAC inhibitors:
Vorinostat (Zolinza®)
Romidepsin (Istodax®)

Chemotherapies (Single & Multi-Agent)
Methotrexate
Pentostatin & other purine analogues (Fludarabine, 2- deoxychloroadenosine)
Liposomal doxorubicin (Doxil®)
Gemcitabine (Gemzar®)
Cyclophosphamide, oral

(CHOP)

Bone marrow / Stem cell transplantation:
Bone marrow/Stem cell
     Allogenic Transplantation

Last updated May, 2009

Additional treatments may be available through clinical trials.